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The following is a list of enemies that the Fantastic Four fought in the Marvel Animated Universe.

List of enemies

Name Photo Powers and equipment
Annihilus
69869789
Cosmic Control Rod
Blastaar
7087908799
Fires energy from his hands
Doctor Doom
780879087958678
Armored suit
Various technological weapons
Dorek Vll
780890475675
Shapeshifting
Ego
87908908905675
Energy blast
Firelord
795675754
Control over fire through the Power Cosmic
Galactus
7808972
Power Cosmic
Hydro-Man
79089708790
Turns his body into water
Krang
8978934535
Super Strength
Breaths under water
Lyja
780708970897
Shapeshifting
Malice
78908908989
Invisibility
Maximus the Mad
567865456456
?
Medusa
7089087586785
"Living hair" that she uses as limbs
Mole Man
89089089578678
?
Psycho-Man
8908956757
Psycho Ray that causes it's victims to feel fear, doubt, or hate
Puppet Master
475767587
Special clay that allows him to control people's minds
Sentry 213
890890567567
?
Super-Skrull
564647567567
Combined powers of the Fantastic Four
Terrax
346346456456
Control over Earth through the Power Cosmic
Trapster
89708905867856
Gun that fires paste
Ulysses Klaw
68768678
Gun that creates destructive sound waves
Later turned into living sound
Warlord Morrat
54754746756
Shapeshifting
Wizard
890080808
Various weapons he invented

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